Matteo Berrettini has been ruled out of Wimbledon after testing positive for COVID-19.
The Italian was one of the favourites for the title having reached last year’s final.
He also picked up two grass court trophies in the build-up to Wimbledon, including Queens.
Writing on Instagram, Berrettini said: “I am heartbroken to announce that I need to withdraw from @wimbledon due to a positive COVID-19 test result.
“I have had flu symptoms and been isolating the last few days. Despite symptoms not being severe, I decided it was important to take another test this morning to protect the health and safety of my fellow competitors and everyone else involved in the tournament.
“I have no words to describe the extreme disappointed I feel. The dream is over for this year, but I will be back stronger. Thank you for the support.”
Berrettini had trained with Nadal on Centre Court just days before his positive test, in the first ever pre-tournament practice to break in the surface.
The Italian even shared a picture of them together on Instagram after they had trained together.
Berrettini, who has been replaced by lucky loser Elias Ymer, was the eighth seed and had been due to face Cristian Garin in the opening match on Court One on Tuesday.
His withdrawal follows that of former finalist Marin Cilic, who announced on Monday that he had also tested positive for COVID-19.
He trained with Novak Djokovic just days before his positive test.
Both players were in Nadal’s half of the draw, with Cilic seeded to be his fourth-round opponent.
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